How they differ
- Melatonin: Hormone-based circadian-timing ingredient
- Magnesium: Essential mineral sometimes marketed for sleep
Melatonin has clearer use-specific evidence for selected timing problems; magnesium sleep evidence is more limited and population-specific.
| Comparison point | Melatonin | Magnesium |
| Common purpose | Hormone-based circadian-timing ingredient | Essential mineral sometimes marketed for sleep |
| Evidence context | Melatonin has clearer use-specific evidence for selected timing problems; magnesium sleep evidence is more limited and population-specific. | Melatonin has clearer use-specific evidence for selected timing problems; magnesium sleep evidence is more limited and population-specific. |
| Common forms | Immediate-release and extended-release tablets, capsules, liquids, gummies, and sublingual products are common. | Glycinate, citrate, oxide, chloride, lactate and other salts |
| Important limitations | Evidence for one form, amount, population or outcome does not prove that every finished product works the same way. | Evidence for one form, amount, population or outcome does not prove that every finished product works the same way. |
| Safety context | Melatonin can cause drowsiness and timing effects; supplemental magnesium can cause gastrointestinal effects. | Melatonin can cause drowsiness and timing effects; supplemental magnesium can cause gastrointestinal effects. |
| Who should be cautious | Pregnancy, breastfeeding, children, seizure disorders, autoimmune conditions, or persistent insomnia warrant professional guidance. | People with kidney disease, unexplained weakness, heart-rhythm problems, or complex medication schedules should seek professional guidance before supplementing. |
Melatonin can cause drowsiness and timing effects; supplemental magnesium can cause gastrointestinal effects.
Read the exact product label and do not use this comparison as personal dosing advice.