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Ingredient comparison

Vitamin D2 vs Vitamin D3

Both can raise vitamin D status; effects can differ by dose and schedule.

Comparison pointVitamin D2Vitamin D3
Common purposeErgocalciferol formCholecalciferol form
Evidence contextBoth can raise vitamin D status; effects can differ by dose and schedule.Both can raise vitamin D status; effects can differ by dose and schedule.
Common formsVitamin D2 and vitamin D3Vitamin D2 and vitamin D3
Important limitationsEvidence for one form, amount, population or outcome does not prove that every finished product works the same way.Evidence for one form, amount, population or outcome does not prove that every finished product works the same way.
Safety contextExcess of either form can cause vitamin D toxicity and high calcium.Excess of either form can cause vitamin D toxicity and high calcium.
Who should be cautiousPeople with kidney disease, granulomatous disease, high calcium, malabsorption, or medicines affecting calcium should obtain professional advice.People with kidney disease, granulomatous disease, high calcium, malabsorption, or medicines affecting calcium should obtain professional advice.

How they differ

  • Vitamin D2: Ergocalciferol form
  • Vitamin D3: Cholecalciferol form

Safety first

Excess of either form can cause vitamin D toxicity and high calcium.

Read the exact product label and do not use this comparison as personal dosing advice.