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Amino Acids

L-Theanine

Chemical / Botanical Synonym: theanine

Evidence Grade Limited or preliminary evidence

Evidence Confidence 70% Validated

Clinical Target Dose Standard Human Clinical Trial Target Dosing Range

Compliance Status FDA DSHEA 1994

1 Core Pharmacological & Chemical Identity

Scientific / Botanical Name theanine

Chemical / Botanical Class Amino Acids Bioactive Standard

Active Bioactive Marker Standardized Active Fraction / High Purity HPLC

Delivery Formats Capsule, Sublingual Liquid, Tablet, Chewable Lozenge

2 Cellular Mechanisms & Biological Outcomes

Primary Cellular Mechanism:

A tea-derived amino acid studied in small trials for relaxation, attention, and sleep-related outcomes, often with caffeine.

Evidence-Backed Outcomes:

Cellular receptor modulation and metabolic signaling balance

Antioxidant defense and inflammation pathway regulation

Support for daily energy, cellular repair, and physiological resilience

3 Sourcing, Bioavailability & Purity Attributes

Origin & Extraction Pharmaceutical / Botanical Grade Extraction & Fermentation

Dietary & Clean Label Status 100% Non-GMO, Gluten-Free, Vegan/Vegetarian Compatible, Heavy Metal Tested

Natural Food Sources Concentrated Dietary & Herbal Matrix

4 Dosage Protocol & Safety Spacing

Clinical Trial Target Dosing

Standard Human Clinical Trial Target Dosing Range

Recommended daily intake adheres to peer-reviewed published human clinical protocols.

Contraindications & Interactions

Consult qualified healthcare professional if pregnant, nursing, or taking prescription therapies.

Verify with Drug-Nutrient Safety Check →

5 Regulatory Standards & Government (.GOV) Index

FDA Regulatory Category DSHEA 1994 Compliant Dietary Ingredient (21 U.S.C. 321(ff))

Manufacturing Standards cGMP 21 CFR Part 111 & ISO 17025 Third-Party Tested

.GOV Primary Government & Peer-Reviewed Study Source:

National Library of Medicine (PubMed / NCBI)

View Official .GOV Study →

Featured Formulations Containing L-Theanine

Verified top-tier dietary supplements formulated with clinical bioactive grades.

View All 51 Products

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L-Theanine Clinical Discussion & Q&A

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